Pediatric heart transplant rejection following COVID-19 infection

BACKGROUND: Infections have been associated with rejection episodes in solid organ transplant recipients. We report an association between COVID-19 infection and heart transplant (HT) rejection. CASE DESCRIPTION: The patient was 14 years old and 6.5 years post-HT. He developed symptoms of rejection...

Descripción completa

Detalles Bibliográficos
Autores principales: Shea, Erin V., Sinicropi, Natalie L., Cusick, Matthew F., Rabah, Raja, Lim, Heang M., Schumacher, Kurt R., McCormick, Amanda D., Peng, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110939/
https://www.ncbi.nlm.nih.gov/pubmed/37188611
http://dx.doi.org/10.1016/j.transproceed.2023.04.021
_version_ 1785027352241111040
author Shea, Erin V.
Sinicropi, Natalie L.
Cusick, Matthew F.
Rabah, Raja
Lim, Heang M.
Schumacher, Kurt R.
McCormick, Amanda D.
Peng, David M.
author_facet Shea, Erin V.
Sinicropi, Natalie L.
Cusick, Matthew F.
Rabah, Raja
Lim, Heang M.
Schumacher, Kurt R.
McCormick, Amanda D.
Peng, David M.
author_sort Shea, Erin V.
collection PubMed
description BACKGROUND: Infections have been associated with rejection episodes in solid organ transplant recipients. We report an association between COVID-19 infection and heart transplant (HT) rejection. CASE DESCRIPTION: The patient was 14 years old and 6.5 years post-HT. He developed symptoms of rejection within two weeks of COVID exposure and presumed infection. CONCLUSIONS: In this case, COVID-19 infection closely preceded significant rejection and graft dysfunction. Further study is needed to establish a correlation between COVID-19 infection and rejection in heart transplant patients.
format Online
Article
Text
id pubmed-10110939
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-101109392023-04-18 Pediatric heart transplant rejection following COVID-19 infection Shea, Erin V. Sinicropi, Natalie L. Cusick, Matthew F. Rabah, Raja Lim, Heang M. Schumacher, Kurt R. McCormick, Amanda D. Peng, David M. Transplant Proc Article BACKGROUND: Infections have been associated with rejection episodes in solid organ transplant recipients. We report an association between COVID-19 infection and heart transplant (HT) rejection. CASE DESCRIPTION: The patient was 14 years old and 6.5 years post-HT. He developed symptoms of rejection within two weeks of COVID exposure and presumed infection. CONCLUSIONS: In this case, COVID-19 infection closely preceded significant rejection and graft dysfunction. Further study is needed to establish a correlation between COVID-19 infection and rejection in heart transplant patients. Elsevier Inc. 2023-04-18 /pmc/articles/PMC10110939/ /pubmed/37188611 http://dx.doi.org/10.1016/j.transproceed.2023.04.021 Text en © 2023 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Shea, Erin V.
Sinicropi, Natalie L.
Cusick, Matthew F.
Rabah, Raja
Lim, Heang M.
Schumacher, Kurt R.
McCormick, Amanda D.
Peng, David M.
Pediatric heart transplant rejection following COVID-19 infection
title Pediatric heart transplant rejection following COVID-19 infection
title_full Pediatric heart transplant rejection following COVID-19 infection
title_fullStr Pediatric heart transplant rejection following COVID-19 infection
title_full_unstemmed Pediatric heart transplant rejection following COVID-19 infection
title_short Pediatric heart transplant rejection following COVID-19 infection
title_sort pediatric heart transplant rejection following covid-19 infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110939/
https://www.ncbi.nlm.nih.gov/pubmed/37188611
http://dx.doi.org/10.1016/j.transproceed.2023.04.021
work_keys_str_mv AT sheaerinv pediatrichearttransplantrejectionfollowingcovid19infection
AT sinicropinataliel pediatrichearttransplantrejectionfollowingcovid19infection
AT cusickmatthewf pediatrichearttransplantrejectionfollowingcovid19infection
AT rabahraja pediatrichearttransplantrejectionfollowingcovid19infection
AT limheangm pediatrichearttransplantrejectionfollowingcovid19infection
AT schumacherkurtr pediatrichearttransplantrejectionfollowingcovid19infection
AT mccormickamandad pediatrichearttransplantrejectionfollowingcovid19infection
AT pengdavidm pediatrichearttransplantrejectionfollowingcovid19infection

Ejemplares similares