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Effect of coronaviruses on blood vessel permeability: potential therapeutic targets

Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pand...

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Detalles Bibliográficos
Autores principales: Machado, Nicolle R., Dias, Karina T., Cortes, Bryan F.S., Rodrigues, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111163/
https://www.ncbi.nlm.nih.gov/pubmed/37067023
http://dx.doi.org/10.1177/17534666231162252
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author Machado, Nicolle R.
Dias, Karina T.
Cortes, Bryan F.S.
Rodrigues, Stephen F.
author_facet Machado, Nicolle R.
Dias, Karina T.
Cortes, Bryan F.S.
Rodrigues, Stephen F.
author_sort Machado, Nicolle R.
collection PubMed
description Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pandemic since HIV/AIDS. This review aimed to bring together important updated aspects related to coronavirus-induced diseases and the enhanced vascular permeability observed mainly in the lungs of affected people. The dysregulated vascular permeability in the lungs is of fundamental importance for coronaviruses-caused morbidity and mortality. Thus, as described in this review, it is a target of new and old drugs.
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spelling pubmed-101111632023-04-18 Effect of coronaviruses on blood vessel permeability: potential therapeutic targets Machado, Nicolle R. Dias, Karina T. Cortes, Bryan F.S. Rodrigues, Stephen F. Ther Adv Respir Dis Review Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pandemic since HIV/AIDS. This review aimed to bring together important updated aspects related to coronavirus-induced diseases and the enhanced vascular permeability observed mainly in the lungs of affected people. The dysregulated vascular permeability in the lungs is of fundamental importance for coronaviruses-caused morbidity and mortality. Thus, as described in this review, it is a target of new and old drugs. SAGE Publications 2023-04-17 /pmc/articles/PMC10111163/ /pubmed/37067023 http://dx.doi.org/10.1177/17534666231162252 Text en © The Author(s), 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Machado, Nicolle R.
Dias, Karina T.
Cortes, Bryan F.S.
Rodrigues, Stephen F.
Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
title Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
title_full Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
title_fullStr Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
title_full_unstemmed Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
title_short Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
title_sort effect of coronaviruses on blood vessel permeability: potential therapeutic targets
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111163/
https://www.ncbi.nlm.nih.gov/pubmed/37067023
http://dx.doi.org/10.1177/17534666231162252
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