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Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pand...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111163/ https://www.ncbi.nlm.nih.gov/pubmed/37067023 http://dx.doi.org/10.1177/17534666231162252 |
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author | Machado, Nicolle R. Dias, Karina T. Cortes, Bryan F.S. Rodrigues, Stephen F. |
author_facet | Machado, Nicolle R. Dias, Karina T. Cortes, Bryan F.S. Rodrigues, Stephen F. |
author_sort | Machado, Nicolle R. |
collection | PubMed |
description | Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pandemic since HIV/AIDS. This review aimed to bring together important updated aspects related to coronavirus-induced diseases and the enhanced vascular permeability observed mainly in the lungs of affected people. The dysregulated vascular permeability in the lungs is of fundamental importance for coronaviruses-caused morbidity and mortality. Thus, as described in this review, it is a target of new and old drugs. |
format | Online Article Text |
id | pubmed-10111163 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-101111632023-04-18 Effect of coronaviruses on blood vessel permeability: potential therapeutic targets Machado, Nicolle R. Dias, Karina T. Cortes, Bryan F.S. Rodrigues, Stephen F. Ther Adv Respir Dis Review Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pandemic since HIV/AIDS. This review aimed to bring together important updated aspects related to coronavirus-induced diseases and the enhanced vascular permeability observed mainly in the lungs of affected people. The dysregulated vascular permeability in the lungs is of fundamental importance for coronaviruses-caused morbidity and mortality. Thus, as described in this review, it is a target of new and old drugs. SAGE Publications 2023-04-17 /pmc/articles/PMC10111163/ /pubmed/37067023 http://dx.doi.org/10.1177/17534666231162252 Text en © The Author(s), 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Machado, Nicolle R. Dias, Karina T. Cortes, Bryan F.S. Rodrigues, Stephen F. Effect of coronaviruses on blood vessel permeability: potential therapeutic targets |
title | Effect of coronaviruses on blood vessel permeability: potential
therapeutic targets |
title_full | Effect of coronaviruses on blood vessel permeability: potential
therapeutic targets |
title_fullStr | Effect of coronaviruses on blood vessel permeability: potential
therapeutic targets |
title_full_unstemmed | Effect of coronaviruses on blood vessel permeability: potential
therapeutic targets |
title_short | Effect of coronaviruses on blood vessel permeability: potential
therapeutic targets |
title_sort | effect of coronaviruses on blood vessel permeability: potential
therapeutic targets |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111163/ https://www.ncbi.nlm.nih.gov/pubmed/37067023 http://dx.doi.org/10.1177/17534666231162252 |
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