Non-coding regions of nuclear-DNA-encoded mitochondrial genes and intergenic sequences are targeted by autoantibodies in breast cancer

Autoantibodies against mitochondrial-derived antigens play a key role in chronic tissue inflammation in autoimmune disorders and cancers. Here, we identify autoreactive nuclear genomic DNA (nDNA)-encoded mitochondrial gene products (GAPDH, PKM2, GSTP1, SPATA5, MFF, TSPOAP1, PHB2, COA4, and HAGH) rec...

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Detalles Bibliográficos
Autores principales: Obaidat, Deya, Giordo, Roberta, Kleinbrink, Erica L., Banisad, Emilia, Grossman, Lawrence I., Arshad, Rooshan, Stark, Azadeh, Maroun, Marie-Claire, Lipovich, Leonard, Fernandez-Madrid, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111166/
https://www.ncbi.nlm.nih.gov/pubmed/37082114
http://dx.doi.org/10.3389/fgene.2022.970619

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