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FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells

Noncanonical exon usage plays many important roles in cellular phenotypes, but its contribution to human B-cell development remains sketchily understood. To fill this gap, we collected various B-cell fractions from bone marrow (BM) and tonsil donors, performed RNA sequencing, and examined transcript...

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Detalles Bibliográficos
Autores principales:	Yang, Scarlett Y., Hayer, Katharina E., Fazelinia, Hossein, Spruce, Lynn A., Asnani, Mukta, Black, Kathryn L., Naqvi, Ammar S., Pillai, Vinodh, Barash, Yoseph, Elenitoba-Johnson, Kojo S. J., Thomas-Tikhonenko, Andrei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2022
Materias:	Lymphoid Neoplasia
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111352/ https://www.ncbi.nlm.nih.gov/pubmed/36322817 http://dx.doi.org/10.1182/bloodadvances.2022007910

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