Total Synthesis and Structure Assignment of the Relacidine Lipopeptide Antibiotics and Preparation of Analogues with Enhanced Stability

[Image: see text] The unabated rise of antibiotic resistance has raised the specter of a post-antibiotic era and underscored the importance of developing new classes of antibiotics. The relacidines are a recently discovered group of nonribosomal lipopeptide antibiotics that show promising activity a...

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Detalles Bibliográficos
Autores principales: Al Ayed, Karol, Zamarbide Losada, Denise, Machushynets, Nataliia V., Terlouw, Barbara, Elsayed, Somayah S., Schill, Julian, Trebosc, Vincent, Pieren, Michel, Medema, Marnix H., van Wezel, Gilles P., Martin, Nathaniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111413/
https://www.ncbi.nlm.nih.gov/pubmed/37000899
http://dx.doi.org/10.1021/acsinfecdis.3c00043

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