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The Dictyostelium discoideum genome lacks significant DNA methylation and uncovers palindromic sequences as a source of false positives in bisulfite sequencing

DNA methylation, the addition of a methyl (CH(3)) group to a cytosine residue, is an evolutionarily conserved epigenetic mark involved in a number of different biological functions in eukaryotes, including transcriptional regulation, chromatin structural organization, cellular differentiation and de...

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Detalles Bibliográficos
Autores principales: Drewell, Robert A, Cormier, Tayla C, Steenwyk, Jacob L, Denis, James St, Tabima, Javier F, Dresch, Jacqueline M, Larochelle, Denis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111430/
https://www.ncbi.nlm.nih.gov/pubmed/37081864
http://dx.doi.org/10.1093/nargab/lqad035