Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a “2‐Hit” Murine Model

BACKGROUND: Recent studies have suggested that cardiac nitrosative stress mediated by pathological overproduction of nitric oxide (NO) via inducible NO synthase (iNOS) contributes to the pathogenesis of heart failure with preserved ejection fraction (HFpEF). Other studies have suggested that endothe...

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Detalles Bibliográficos
Autores principales: LaPenna, Kyle B., Li, Zhen, Doiron, Jake E., Sharp, Thomas E., Xia, Huijing, Moles, Karl, Koul, Kashyap, Wang, John S., Polhemus, David J., Goodchild, Traci T., Patel, Ravi B., Shah, Sanjiv J., Lefer, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111505/
https://www.ncbi.nlm.nih.gov/pubmed/36752224
http://dx.doi.org/10.1161/JAHA.122.028480

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