Krüppel‐Like Factors Orchestrate Endothelial Gene Expression Through Redundant and Non‐Redundant Enhancer Networks

BACKGROUND: Proper function of endothelial cells is critical for vascular integrity and organismal survival. Studies over the past 2 decades have identified 2 members of the KLF (Krüppel‐like factor) family of proteins, KLF2 and KLF4, as nodal regulators of endothelial function. Strikingly, inducibl...

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Detalles Bibliográficos
Autores principales: Sweet, David R., Padmanabhan, Roshan, Liao, Xudong, Dashora, Himanshu R., Tang, Xinmiao, Nayak, Lalitha, Jain, Rajan, De Val, Sarah, Vinayachandran, Vinesh, Jain, Mukesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111506/
https://www.ncbi.nlm.nih.gov/pubmed/36789992
http://dx.doi.org/10.1161/JAHA.121.024303

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