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NOD-like receptor NLRC5 promotes neuroinflammation and inhibits neuronal survival in Parkinson’s disease models

Parkinson’s disease (PD) is mainly characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and neuroinflammation mediated by overactivated microglia and astrocytes. NLRC5 (nucleotide-binding oligomerization domain-like receptor family caspas...

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Detalles Bibliográficos
Autores principales: Liu, Zhaolin, Shen, Chenye, Li, Heng, Tong, Jiabin, Wu, Yufei, Ma, Yuanyuan, Wang, Jinghui, Wang, Zishan, Li, Qing, Zhang, Xiaoshuang, Dong, Hongtian, Yang, Yufang, Yu, Mei, Wang, Jian, Zhou, Renyuan, Fei, Jian, Huang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111753/
https://www.ncbi.nlm.nih.gov/pubmed/37072793
http://dx.doi.org/10.1186/s12974-023-02755-4

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