Cargando…

Screening antivirals with a mCherry-expressing recombinant bovine respiratory syncytial virus: a proof of concept using cyclopamine

Bovine respiratory syncytial virus (BRSV) is a pathogenic pneumovirus and a major cause of acute respiratory infections in calves. Although different vaccines are available against BRSV, their efficiency remains limited, and no efficient and large-scale treatment exists. Here, we developed a new rev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fix, Jenna, Descamps, Delphyne, Galloux, Marie, Ferret, Cécile, Bouguyon, Edwige, Zohari, Siamak, Näslund, Katarina, Hägglund, Sara, Altmeyer, Ralf, Valarcher, Jean-François, Riffault, Sabine, Eléouët, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111787/ https://www.ncbi.nlm.nih.gov/pubmed/37069656 http://dx.doi.org/10.1186/s13567-023-01165-x

Ejemplares similares

Hardening of Respiratory Syncytial Virus Inclusion Bodies by Cyclopamine Proceeds through Perturbation of the Interactions of the M2-1 Protein with RNA and the P Protein
por: Diot, Cédric, et al.
Publicado: (2023)

A bovine respiratory syncytial virus model with high clinical expression in calves with specific passive immunity
por: Blodörn, Krister, et al.
Publicado: (2015)

Evaluating the potential of whole-genome sequencing for tracing transmission routes in experimental infections and natural outbreaks of bovine respiratory syncytial virus
por: Johnson, Paul C. D., et al.
Publicado: (2022)

The Insertion of Fluorescent Proteins in a Variable Region of Respiratory Syncytial Virus L Polymerase Results in Fluorescent and Functional Enzymes But with Reduced Activities
por: Fix, Jenna, et al.
Publicado: (2011)

Control of IFN-I responses by the aminopeptidase IRAP in neonatal C57BL/6 alveolar macrophages during RSV infection
por: Drajac, Carole, et al.
Publicado: (2021)

Vaccine Safety and Efficacy Evaluation of a Recombinant Bovine Respiratory Syncytial Virus (BRSV) with Deletion of the SH Gene and Subunit Vaccines Based On Recombinant Human RSV Proteins: N-nanorings, P and M2-1, in Calves with Maternal Antibodies
por: Blodörn, Krister, et al.
Publicado: (2014)

Hyper-Enriched Anti-RSV Immunoglobulins Nasally Administered: A Promising Approach for Respiratory Syncytial Virus Prophylaxis
por: Jacque, Emilie, et al.
Publicado: (2021)

Longitudinal study of the immune response and memory following natural bovine respiratory syncytial virus infections in cattle of different age
por: Hägglund, Sara, et al.
Publicado: (2022)

Pulmonary Susceptibility of Neonates to Respiratory Syncytial Virus Infection: A Problem of Innate Immunity?
por: Drajac, Carole, et al.
Publicado: (2017)

Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus—Insights in pathogenesis and perspectives for new treatments
por: Hägglund, Sara, et al.
Publicado: (2017)

Minimal Elements Required for the Formation of Respiratory Syncytial Virus Cytoplasmic Inclusion Bodies In Vivo and In Vitro
por: Galloux, Marie, et al.
Publicado: (2020)

Construction of Two mCherry Plasmids (pXG-mCherry) for Transgenic Leishmania: Valuable Tools for Future Molecular Analysis
por: Vacas, Andrés, et al.
Publicado: (2017)

Regulatory B Lymphocytes Colonize the Respiratory Tract of Neonatal Mice and Modulate Immune Responses of Alveolar Macrophages to RSV Infection in IL-10-Dependant Manner
por: Laubreton, Daphné, et al.
Publicado: (2020)

Visualizing the replication of respiratory syncytial virus in cells and in living mice
por: Rameix-Welti, Marie-Anne, et al.
Publicado: (2014)

New Look at RSV Infection: Tissue Clearing and 3D Imaging of the Entire Mouse Lung at Cellular Resolution
por: Frétaud, Maxence, et al.
Publicado: (2021)

Detection of Influenza D-Specific Antibodies in Bulk Tank Milk from Swedish Dairy Farms
por: Alvarez, Ignacio, et al.
Publicado: (2023)

Structural landscape of the respiratory syncytial virus nucleocapsids
por: Gonnin, Lorène, et al.
Publicado: (2023)

Immunohistochemical amplification of mCherry fusion protein is necessary for proper visualization
por: Falcy, B.A., et al.
Publicado: (2020)

Identification of the translational start site of codon-optimized mCherry in Mycobacterium tuberculosis
por: Carroll, Paul, et al.
Publicado: (2014)

Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies
por: Liang, Hui, et al.
Publicado: (2023)

Development of AlissAID system targeting GFP or mCherry fusion protein
por: Ogawa, Yoshitaka, et al.
Publicado: (2023)

Importance of RNA length for in vitro encapsidation by the nucleoprotein of human respiratory syncytial virus
por: Gonnin, Lorène, et al.
Publicado: (2022)

The respiratory syncytial virus nucleoprotein–RNA complex forms a left-handed helical nucleocapsid
por: Bakker, Saskia E., et al.
Publicado: (2013)

Stage-specific fluorescence intensity of GFP and mCherry during sporulation In Bacillus Subtilis
por: Doherty, Geoff P, et al.
Publicado: (2010)

Tracking Cholesterol/Sphingomyelin-Rich Membrane Domains with the Ostreolysin A-mCherry Protein
por: Skočaj, Matej, et al.
Publicado: (2014)

Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry
por: Wider, Diana, et al.
Publicado: (2017)

Rolling Circle Mutagenesis of GST-mCherry to Understand Mutation, Gene Expression, and Regulation
por: Cole, Jessica, et al.
Publicado: (2017)

mCherry fusions enable the subcellular localization of periplasmic and cytoplasmic proteins in Xanthomonas sp.
por: Pena, Michelle Mendonça, et al.
Publicado: (2020)

mCherry contains a fluorescent protein isoform that interferes with its reporter function
por: Fages-Lartaud, Maxime, et al.
Publicado: (2022)

Fitness of mCherry Reporter Tick-Borne Encephalitis Virus in Tick Experimental Models
por: Kevély, Ádám, et al.
Publicado: (2022)

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
por: Sesterhenn, Fabian, et al.
Publicado: (2019)

Sub-Nucleocapsid Nanoparticles: A Nasal Vaccine against Respiratory Syncytial Virus
por: Roux, Xavier, et al.
Publicado: (2008)

Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity
por: Zhivaki, Dania, et al.
Publicado: (2017)

Cell Wall Antibiotics Provoke Accumulation of Anchored mCherry in the Cross Wall of Staphylococcus aureus
por: Yu, Wenqi, et al.
Publicado: (2012)

Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry
por: Brauchle, Michael, et al.
Publicado: (2014)

Tagging of the vaccinia virus protein F13 with mCherry causes aberrant virion morphogenesis
por: Carpentier, David C. J., et al.
Publicado: (2017)

Engineering of mCherry variants with long Stokes shift, red-shifted fluorescence, and low cytotoxicity
por: Shen, Yi, et al.
Publicado: (2017)

Expression of a Malassezia Codon Optimized mCherry Fluorescent Protein in a Bicistronic Vector
por: Goh, Joleen P. Z., et al.
Publicado: (2020)

An endogenous mCherry-tagged COSA-1 as a crossover investigation tool in Caenorhabditis elegans
por: Ezechukwu, Chiemekam Samuel, et al.
Publicado: (2022)

Use of the mCherry fluorescent protein to optimize the expression of class I lanthipeptides in Escherichia coli
por: Van Zyl, Winschau F, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1r8odp3ok83e60dac1m9b5a6u7