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Adaptation to spindle assembly checkpoint inhibition through the selection of specific aneuploidies

Both the presence of an abnormal complement of chromosomes (aneuploidy) and an increased frequency of chromosome missegregation (chromosomal instability) are hallmarks of cancer. Analyses of cancer genome data have identified certain aneuploidy patterns in tumors; however, the bases behind their sel...

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Detalles Bibliográficos
Autores principales: Adell, Manuel Alonso Y, Klockner, Tamara C., Höfler, Rudolf, Wallner, Lea, Schmid, Julia, Markovic, Ana, Martyniak, Anastasiia, Campbell, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111865/
https://www.ncbi.nlm.nih.gov/pubmed/36859339
http://dx.doi.org/10.1101/gad.350182.122