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Aneuploidy Is Associated with Azole Resistance in Aspergillus fumigatus

Azole resistance in Aspergillus fumigatus is on the rise. Nontarget-mediated mechanisms are a common cause of azole resistance in chronic pulmonary aspergillosis (CPA). Here, we investigate resistance mechanisms using whole-genome sequencing. Sixteen azole-resistant A. fumigatus isolates from CPA we...

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Detalles Bibliográficos
Autores principales: Khateb, Aiah, Gago, Sara, Bromley, Michael, Richardson, Malcom, Bowyer, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112202/
https://www.ncbi.nlm.nih.gov/pubmed/36975834
http://dx.doi.org/10.1128/aac.01253-22