Absorption, Metabolism, and Excretion of [(14)C]-Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Male Subjects

Tebipenem pivoxil hydrobromide (TBP-PI-HBr) is an oral prodrug of pharmacologically active moiety tebipenem (TBP), which is a carbapenem with activity against multidrug-resistant Gram-negative pathogens. Conversion from the prodrug to the active moiety, namely, TBP, occurs in the enterocytes of the...

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Detalles Bibliográficos
Autores principales: Gupta, Vipul K., Maier, Gary, Gasink, Leanne, Ek, Amanda, Fudeman, Mary, Srivastava, Praveen, Talley, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112213/
https://www.ncbi.nlm.nih.gov/pubmed/36995239
http://dx.doi.org/10.1128/aac.01509-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112213/
https://www.ncbi.nlm.nih.gov/pubmed/36995239
http://dx.doi.org/10.1128/aac.01509-22

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