Assessment of neurotransmitter release in human iPSC-derived neuronal/glial cells: a missing in vitro assay for regulatory developmental neurotoxicity testing

Human induced pluripotent stem cell (hiPSC)-derived neural stem cells (NSCs) and their differentiated neuronal/glial derivatives have been recently considered suitable to assess in vitro developmental neurotoxicity (DNT) triggered by exposure to environmental chemicals. The use of human-relevant tes...

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Detalles Bibliográficos
Autores principales: Cervetto, Chiara, Pistollato, Francesca, Amato, Sarah, Mendoza-de Gyves, Emilio, Bal-Price, Anna, Maura, Guido, Marcoli, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon In Cooperation With The Reproductive Toxicology Center 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112275/
https://www.ncbi.nlm.nih.gov/pubmed/36863571
http://dx.doi.org/10.1016/j.reprotox.2023.108358

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