Important Barriers to COVID-19 Vaccination Among African Americans in Black Belt Region

BACKGROUND: To identify important barriers to COVID-19 vaccination among African Americans living in the Black Belt region. METHODS: A cross-sectional, web-based questionnaire survey was conducted using best–worst scaling case 1 (the object case). Thirty-two potential barriers to COVID-19 vaccination were identified from the literature and confirmed by an expert. A nested balanced incomplete block design was used to generate 62 sets of 16 choice tasks. Each choice task included six barriers. Participants were asked to choose the most and least important barriers to their COVID-19 vaccination in each choice task of one set. The natural logarithm of the square root of best counts divided by the worst counts of each barrier was calculated to rank the importance of barriers. RESULTS: Responses from a total of 808 participants were included. Among 32 barriers to COVID-19 vaccination, the five most important barriers were “safety concern of COVID-19 vaccines,” “rapid mutation of COVID-19,” “ingredients of COVID-19 vaccines,” “Emergency Use Authorization (Fast-track approval) of COVID-19 vaccines,” and “inconsistent information of COVID-19 vaccines.” On the other hand, the five least important barriers were “religious reasons,” “lack of time to get COVID-19 vaccine,” “no support from my family and friends,” “political reasons,” and “fear of the needle.” CONCLUSIONS: Important barriers to the COVID-19 vaccination for African Americans living in the Black Belt region centered around the issues that could be resolved by communication strategies. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40615-023-01583-9.