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Pitavastatin Induces Apoptosis of Cutaneous Squamous Cell Carcinoma Cells through Geranylgeranyl Pyrophosphate-Dependent c-Jun N-Terminal Kinase Activation

BACKGROUND: Pitavastatin is a cholesterol-lowering drug and is widely used clinically. In addition to this effect, pitavastatin has shown the potential to induce apoptosis in cutaneous squamous cell carcinoma (SCC) cells. OBJECTIVE: The purpose of this study is to investigate the effects and possibl...

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Detalles Bibliográficos
Autores principales: Kim, Kyung-Il, Kim, Seung-Mee, Lee, Young-Yoon, Lee, Young, Kim, Chang-Deok, Yoon, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112368/
https://www.ncbi.nlm.nih.gov/pubmed/37041705
http://dx.doi.org/10.5021/ad.22.139