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Spastin is an essential regulator of male meiosis, acrosome formation, manchette structure and nuclear integrity

The development and function of male gametes is dependent on a dynamic microtubule network, yet how this is regulated remains poorly understood. We have recently shown that microtubule severing, via the action of the meiotic AAA ATPase protein clade, plays a crucial role in this process. Here, we so...

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Detalles Bibliográficos
Autores principales: Cheers, Samuel R., O'Connor, Anne E., Johnson, Travis K., Merriner, D. Jo, O'Bryan, Moira K., Dunleavy, Jessica E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112905/
https://www.ncbi.nlm.nih.gov/pubmed/36971361
http://dx.doi.org/10.1242/dev.201183