Stress-induced phase separation of ERES components into Sec bodies precedes ER exit inhibition in mammalian cells

Phase separation of components of ER exit sites (ERES) into membraneless compartments, the Sec bodies, occurs in Drosophila cells upon exposure to specific cellular stressors, namely, salt stress and amino acid starvation, and their formation is linked to the early secretory pathway inhibition. Here...

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Detalles Bibliográficos
Autores principales: van Leeuwen, Wessel, Nguyen, Dan T. M., Grond, Rianne, Veenendaal, Tineke, Rabouille, Catherine, Farías, Ginny G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112967/
https://www.ncbi.nlm.nih.gov/pubmed/36325988
http://dx.doi.org/10.1242/jcs.260294

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