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SARS-CoV-2 infection alkalinizes the ERGIC and lysosomes through the viroporin activity of the viral envelope protein

The coronavirus SARS-CoV-2, the agent of the deadly COVID-19 pandemic, is an enveloped virus propagating within the endocytic and secretory organelles of host mammalian cells. Enveloped viruses modify the ionic homeostasis of organelles to render their intra-luminal milieu permissive for viral entry...

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Detalles Bibliográficos
Autores principales:	Wang, Wen-An, Carreras-Sureda, Amado, Demaurex, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112968/ https://www.ncbi.nlm.nih.gov/pubmed/36807531 http://dx.doi.org/10.1242/jcs.260685

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