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Alternative splicing of HDAC7 regulates its interaction with 14-3-3 proteins to alter histone marks and target gene expression

Chromatin regulation and alternative splicing are both critical mechanisms guiding gene expression. Studies have demonstrated that histone modifications can influence alternative splicing decisions, but less is known about how alternative splicing may impact chromatin. Here, we demonstrate that seve...

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Detalles Bibliográficos
Autores principales: Agosto, Laura M., Mallory, Michael J., Ferretti, Max B., Blake, Davia, Krick, Keegan S., Gazzara, Matthew R., Garcia, Benjamin A., Lynch, Kristen W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113009/
https://www.ncbi.nlm.nih.gov/pubmed/36933216
http://dx.doi.org/10.1016/j.celrep.2023.112273