MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases

This report presents an extremely rare case of MAML2-rearranged primary central mucoepidermoid carcinoma (MEC) of the mandible that was discovered as an incidental finding. Our review of the literature identified 36 cases of MAML2-rearranged intraosseous lesions of the jaw (30 central MECs, 5 odonto...

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Autores principales: Aguirre, Sarah E., Tyler, Donald, Owosho, Adepitan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113058/
https://www.ncbi.nlm.nih.gov/pubmed/37082423
http://dx.doi.org/10.1155/2023/7764292
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author Aguirre, Sarah E.
Tyler, Donald
Owosho, Adepitan A.
author_facet Aguirre, Sarah E.
Tyler, Donald
Owosho, Adepitan A.
author_sort Aguirre, Sarah E.
collection PubMed
description This report presents an extremely rare case of MAML2-rearranged primary central mucoepidermoid carcinoma (MEC) of the mandible that was discovered as an incidental finding. Our review of the literature identified 36 cases of MAML2-rearranged intraosseous lesions of the jaw (30 central MECs, 5 odontogenic cysts with mucous prosoplasia, and 1 glandular odontogenic cyst). Given the therapeutic indications for a diagnosis of MEC (a malignant neoplasm), MAML2 rearrangement should be confirmed in suspected cases of central MEC.
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spelling pubmed-101130582023-04-19 MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases Aguirre, Sarah E. Tyler, Donald Owosho, Adepitan A. Case Rep Dent Case Report This report presents an extremely rare case of MAML2-rearranged primary central mucoepidermoid carcinoma (MEC) of the mandible that was discovered as an incidental finding. Our review of the literature identified 36 cases of MAML2-rearranged intraosseous lesions of the jaw (30 central MECs, 5 odontogenic cysts with mucous prosoplasia, and 1 glandular odontogenic cyst). Given the therapeutic indications for a diagnosis of MEC (a malignant neoplasm), MAML2 rearrangement should be confirmed in suspected cases of central MEC. Hindawi 2023-04-11 /pmc/articles/PMC10113058/ /pubmed/37082423 http://dx.doi.org/10.1155/2023/7764292 Text en Copyright © 2023 Sarah E. Aguirre et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Aguirre, Sarah E.
Tyler, Donald
Owosho, Adepitan A.
MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases
title MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases
title_full MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases
title_fullStr MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases
title_full_unstemmed MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases
title_short MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases
title_sort maml2-rearranged primary central mucoepidermoid carcinoma of the mandible as an incidental finding: a case report and review of the literature of molecularly confirmed cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113058/
https://www.ncbi.nlm.nih.gov/pubmed/37082423
http://dx.doi.org/10.1155/2023/7764292
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