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Celastrol Treatment Ameliorated Acute Ischemic Stroke-Induced Brain Injury by Microglial Injury Inhibition and Nrf2/HO-1 Pathway Activations

BACKGROUND: Stroke is the third main reason of mortality, which is the leading reason for adult disability in the globe. Poststroke inflammation is well known to cause acute ischemic stroke- (AIS-) induced brain injury (BI) exacerbation. Celastrol (CL) has exhibited anti-inflammatory activities in v...

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Detalles Bibliográficos
Autores principales:	Cao, Fanfan, Wang, Ying, Song, Yuting, Xu, Fengxia, Xie, Qiuhua, Jiang, Mei, Liu, Xinghui, Zhang, Denghai, Xu, Limin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113063/ https://www.ncbi.nlm.nih.gov/pubmed/37082194 http://dx.doi.org/10.1155/2023/1076522

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