The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities

The DNA-repair capacity in somatic cells is limited compared with that in germ cells. It has remained unknown whether not only lesion-type-specific, but overall repair capacities could be improved. Here we show that the DREAM repressor complex curbs the DNA-repair capacities in somatic tissues of Ca...

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Detalles Bibliográficos
Autores principales: Bujarrabal-Dueso, Arturo, Sendtner, Georg, Meyer, David H., Chatzinikolaou, Georgia, Stratigi, Kalliopi, Garinis, George A., Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113156/
https://www.ncbi.nlm.nih.gov/pubmed/36959262
http://dx.doi.org/10.1038/s41594-023-00942-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113156/
https://www.ncbi.nlm.nih.gov/pubmed/36959262
http://dx.doi.org/10.1038/s41594-023-00942-8

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