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Plasmepsin X activates the PCRCR complex of Plasmodium falciparum by processing PfRh5 for erythrocyte invasion

Plasmodium falciparum causes the most severe form of malaria in humans. The protozoan parasite develops within erythrocytes to mature schizonts, that contain more than 16 merozoites, which egress and invade fresh erythrocytes. The aspartic protease plasmepsin X (PMX), processes proteins and protease...

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Detalles Bibliográficos
Autores principales: Triglia, Tony, Scally, Stephen W., Seager, Benjamin A., Pasternak, Michał, Dagley, Laura F., Cowman, Alan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113190/
https://www.ncbi.nlm.nih.gov/pubmed/37072430
http://dx.doi.org/10.1038/s41467-023-37890-2