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Evaluation of cases with hypersensitivity pneumonia: 10 year analysis

INTRODUCTION: The aim of this study was to examine the clinical features of hypersensitivity pneumonia (HP) cases, diagnostic methods, and related conditions in our hospital, which is a reference clinic in Turkey for chest disease. METHODS: The population of this retrospective cross‐sectional study...

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Autores principales: Koyuncu, Adem, Sarı, Gülden, Şimşek, Ceprail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113273/
https://www.ncbi.nlm.nih.gov/pubmed/36780898
http://dx.doi.org/10.1111/crj.13598
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author Koyuncu, Adem
Sarı, Gülden
Şimşek, Ceprail
author_facet Koyuncu, Adem
Sarı, Gülden
Şimşek, Ceprail
author_sort Koyuncu, Adem
collection PubMed
description INTRODUCTION: The aim of this study was to examine the clinical features of hypersensitivity pneumonia (HP) cases, diagnostic methods, and related conditions in our hospital, which is a reference clinic in Turkey for chest disease. METHODS: The population of this retrospective cross‐sectional study consists of all hypersensitivity pneumonia patients followed in a tertiary hospital between 2010 and 2019. The data of 78 patients were included in the analysis. Data were grouped by source of exposure (occupational, environmental, and cryptogenic) by examining the files of the patients. RESULTS: Occupational risk factors were detected in 29 (37.2%) of the cases, environmental risk factors were found in 24 (30.8%) cases, neither occupational nor environmental risk factors were detected in 25 (32%) cases, and they were evaluated as cryptogenic. The time from the onset of symptoms to diagnosis was 15.8 ± 26.6 months. The time from the onset of symptoms to diagnosis was found to be longer in the group with occupational risk factors compared with the other groups and was statistically significant (0.044). CONCLUSION: HP is a immune‐mediated interstitial lung disease induced by repeated exposure to environmental and occupational antigens. Etiological agent can be detected in HP patients by detailed questioning of occupational and environmental exposure that may be associated with the onset of symptoms in cases with suspected HP.
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spelling pubmed-101132732023-04-20 Evaluation of cases with hypersensitivity pneumonia: 10 year analysis Koyuncu, Adem Sarı, Gülden Şimşek, Ceprail Clin Respir J Original Articles INTRODUCTION: The aim of this study was to examine the clinical features of hypersensitivity pneumonia (HP) cases, diagnostic methods, and related conditions in our hospital, which is a reference clinic in Turkey for chest disease. METHODS: The population of this retrospective cross‐sectional study consists of all hypersensitivity pneumonia patients followed in a tertiary hospital between 2010 and 2019. The data of 78 patients were included in the analysis. Data were grouped by source of exposure (occupational, environmental, and cryptogenic) by examining the files of the patients. RESULTS: Occupational risk factors were detected in 29 (37.2%) of the cases, environmental risk factors were found in 24 (30.8%) cases, neither occupational nor environmental risk factors were detected in 25 (32%) cases, and they were evaluated as cryptogenic. The time from the onset of symptoms to diagnosis was 15.8 ± 26.6 months. The time from the onset of symptoms to diagnosis was found to be longer in the group with occupational risk factors compared with the other groups and was statistically significant (0.044). CONCLUSION: HP is a immune‐mediated interstitial lung disease induced by repeated exposure to environmental and occupational antigens. Etiological agent can be detected in HP patients by detailed questioning of occupational and environmental exposure that may be associated with the onset of symptoms in cases with suspected HP. John Wiley and Sons Inc. 2023-02-13 /pmc/articles/PMC10113273/ /pubmed/36780898 http://dx.doi.org/10.1111/crj.13598 Text en © 2023 The Authors. The Clinical Respiratory Journal published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Koyuncu, Adem
Sarı, Gülden
Şimşek, Ceprail
Evaluation of cases with hypersensitivity pneumonia: 10 year analysis
title Evaluation of cases with hypersensitivity pneumonia: 10 year analysis
title_full Evaluation of cases with hypersensitivity pneumonia: 10 year analysis
title_fullStr Evaluation of cases with hypersensitivity pneumonia: 10 year analysis
title_full_unstemmed Evaluation of cases with hypersensitivity pneumonia: 10 year analysis
title_short Evaluation of cases with hypersensitivity pneumonia: 10 year analysis
title_sort evaluation of cases with hypersensitivity pneumonia: 10 year analysis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113273/
https://www.ncbi.nlm.nih.gov/pubmed/36780898
http://dx.doi.org/10.1111/crj.13598
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