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Role of different recombinant PrP substrates in the diagnostic accuracy of the CSF RT-QuIC assay in Creutzfeldt-Jakob disease

The development of the real-time quaking-induced conversion (RT-QuIC), an in vitro protein misfolding amplification assay, was an innovation in the scientific field of protein misfolding diseases. In prion diseases, these types of assays imitate the pathological conversion of the cellular prion prot...

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Detalles Bibliográficos
Autores principales:	Da Silva Correia, Susana Margarida, Schmitz, Matthias, Fischer, Andre, Hermann, Peter, Zerr, Inga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113290/ https://www.ncbi.nlm.nih.gov/pubmed/36536226 http://dx.doi.org/10.1007/s00441-022-03715-9

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