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Prion strains viewed through the lens of cryo-EM

Mammalian prions are lethal transmissible pathogens that cause fatal neurodegenerative diseases in humans and animals. They consist of fibrils of misfolded, host-encoded prion protein (PrP) which propagate through templated protein polymerisation. Prion strains produce distinct clinicopathological p...

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Detalles Bibliográficos
Autores principales:	Manka, Szymon W., Wenborn, Adam, Collinge, John, Wadsworth, Jonathan D. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113314/ https://www.ncbi.nlm.nih.gov/pubmed/36028585 http://dx.doi.org/10.1007/s00441-022-03676-z

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