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Exploring potential molecular resistance and clonal evolution in advanced HER2-positive gastric cancer under trastuzumab therapy

HER2-positive gastric cancer (GC) makes up 15–20% of all GC incidences, and targeted therapy with trastuzumab is the standard of treatment. However, the mechanisms of resistance to trastuzumab are still not fully understood and presents a significant challenge in clinical practice. In this study, wh...

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Detalles Bibliográficos
Autores principales:	Xu, Qi, Xu, Xiaoqing, Tang, Haimeng, Yan, Junrong, Li, Jingjing, Bao, Hua, Wu, Xue, Shao, Yang, Luo, Cong, Wen, Haimin, Jin, Jianying, Ying, Jieer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113330/ https://www.ncbi.nlm.nih.gov/pubmed/37072406 http://dx.doi.org/10.1038/s41389-023-00466-2

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