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Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture

PURPOSE: Pre-operative scores based on patient characteristics are commonly used to predict hip fracture outcomes. Mobility, an indicator of pre-operative function, has been neglected as a potential predictor. We assessed the ability of pre-fracture mobility to predict post-operative outcomes follow...

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Autores principales: Stubbs, Thomas A., Doherty, William J., Chaplin, Andrew, Langford, Sarah, Reed, Mike R., Sayer, Avan A., Witham, Miles D., Sorial, Antony K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113355/
https://www.ncbi.nlm.nih.gov/pubmed/37002428
http://dx.doi.org/10.1007/s41999-023-00767-0
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author Stubbs, Thomas A.
Doherty, William J.
Chaplin, Andrew
Langford, Sarah
Reed, Mike R.
Sayer, Avan A.
Witham, Miles D.
Sorial, Antony K.
author_facet Stubbs, Thomas A.
Doherty, William J.
Chaplin, Andrew
Langford, Sarah
Reed, Mike R.
Sayer, Avan A.
Witham, Miles D.
Sorial, Antony K.
author_sort Stubbs, Thomas A.
collection PubMed
description PURPOSE: Pre-operative scores based on patient characteristics are commonly used to predict hip fracture outcomes. Mobility, an indicator of pre-operative function, has been neglected as a potential predictor. We assessed the ability of pre-fracture mobility to predict post-operative outcomes following hip fracture. METHODS: We analysed prospectively collected data from hip fracture surgery patients at a large-volume trauma unit. Mobility was classified into four groups. Post-operative outcomes studied were mortality and residence at 30 days, medical complications within 30- or 60-days post-operatively, and prolonged length of stay (LOS, ≥ 28 days). We performed multivariate regression analyses adjusting for age and sex to assess the discriminative ability of the Nottingham Hip Fracture Score (NHFS), with and without mobility, for predicting outcomes using the area under the receiver operating characteristic curve (AUROC). RESULTS: 1919 patients were included, mean age 82.6 (SD 8.2); 1357 (70.7%) were women. Multivariate analysis demonstrated patients with worse mobility had a 1.7–5.5-fold higher 30-day mortality (p ≤ 0.001), and 1.9–3.2-fold higher likelihood of prolonged LOS (p ≤ 0.001). Worse mobility was associated with a 2.3–3.8-fold higher likelihood of living in a care home at 30-days post-operatively (p < 0.001) and a 1.3–2.0-fold higher likelihood of complications within 30 days (p ≤ 0.001). Addition of mobility improved NHFS discrimination for discharge location, AUROC NHFS 0.755 [0.733–0.777] to NHFS + mobility 0.808 [0.789–0.828], and LOS, AUROC NHFS 0.584 [0.557–0.611] to NHFS + mobility 0.616 [0.590–0.643]. CONCLUSION: Incorporating mobility assessment into risk scores may improve casemix adjustment, prognostication following hip fracture, and identify high-risk patient groups requiring enhanced post-operative care at admission. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s41999-023-00767-0.
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spelling pubmed-101133552023-04-20 Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture Stubbs, Thomas A. Doherty, William J. Chaplin, Andrew Langford, Sarah Reed, Mike R. Sayer, Avan A. Witham, Miles D. Sorial, Antony K. Eur Geriatr Med Research Paper PURPOSE: Pre-operative scores based on patient characteristics are commonly used to predict hip fracture outcomes. Mobility, an indicator of pre-operative function, has been neglected as a potential predictor. We assessed the ability of pre-fracture mobility to predict post-operative outcomes following hip fracture. METHODS: We analysed prospectively collected data from hip fracture surgery patients at a large-volume trauma unit. Mobility was classified into four groups. Post-operative outcomes studied were mortality and residence at 30 days, medical complications within 30- or 60-days post-operatively, and prolonged length of stay (LOS, ≥ 28 days). We performed multivariate regression analyses adjusting for age and sex to assess the discriminative ability of the Nottingham Hip Fracture Score (NHFS), with and without mobility, for predicting outcomes using the area under the receiver operating characteristic curve (AUROC). RESULTS: 1919 patients were included, mean age 82.6 (SD 8.2); 1357 (70.7%) were women. Multivariate analysis demonstrated patients with worse mobility had a 1.7–5.5-fold higher 30-day mortality (p ≤ 0.001), and 1.9–3.2-fold higher likelihood of prolonged LOS (p ≤ 0.001). Worse mobility was associated with a 2.3–3.8-fold higher likelihood of living in a care home at 30-days post-operatively (p < 0.001) and a 1.3–2.0-fold higher likelihood of complications within 30 days (p ≤ 0.001). Addition of mobility improved NHFS discrimination for discharge location, AUROC NHFS 0.755 [0.733–0.777] to NHFS + mobility 0.808 [0.789–0.828], and LOS, AUROC NHFS 0.584 [0.557–0.611] to NHFS + mobility 0.616 [0.590–0.643]. CONCLUSION: Incorporating mobility assessment into risk scores may improve casemix adjustment, prognostication following hip fracture, and identify high-risk patient groups requiring enhanced post-operative care at admission. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s41999-023-00767-0. Springer International Publishing 2023-03-31 2023 /pmc/articles/PMC10113355/ /pubmed/37002428 http://dx.doi.org/10.1007/s41999-023-00767-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Paper
Stubbs, Thomas A.
Doherty, William J.
Chaplin, Andrew
Langford, Sarah
Reed, Mike R.
Sayer, Avan A.
Witham, Miles D.
Sorial, Antony K.
Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture
title Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture
title_full Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture
title_fullStr Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture
title_full_unstemmed Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture
title_short Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture
title_sort using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113355/
https://www.ncbi.nlm.nih.gov/pubmed/37002428
http://dx.doi.org/10.1007/s41999-023-00767-0
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