Lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology

Some biologically active substances are unstable and poorly soluble in aqueous media, at the same time exhibiting low bioavailability. The incorporation of these biologically active compounds into the structure of a lipid-based lyotropic liquid crystalline phase or nanoparticles can increase or impr...

Descripción completa

Detalles Bibliográficos
Autores principales: Zatloukalova, Martina, Poltorak, Lukasz, Bilewicz, Renata, Vacek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113356/
https://www.ncbi.nlm.nih.gov/pubmed/37071228
http://dx.doi.org/10.1007/s00604-023-05727-w
_version_ 1785027822228602880
author Zatloukalova, Martina
Poltorak, Lukasz
Bilewicz, Renata
Vacek, Jan
author_facet Zatloukalova, Martina
Poltorak, Lukasz
Bilewicz, Renata
Vacek, Jan
author_sort Zatloukalova, Martina
collection PubMed
description Some biologically active substances are unstable and poorly soluble in aqueous media, at the same time exhibiting low bioavailability. The incorporation of these biologically active compounds into the structure of a lipid-based lyotropic liquid crystalline phase or nanoparticles can increase or improve their stability and transport properties, subsequent bioavailability, and applicability in general. The aim of this short overview is (1) to clarify the principle of self-assembly of lipidic amphiphilic molecules in an aqueous environment and (2) to present lipidic bicontinuous cubic and hexagonal phases and their current biosensing (with a focus on electrochemical protocols) and biomedical applications. GRAPHICAL ABSTRACT: [Image: see text]
format Online
Article
Text
id pubmed-10113356
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Vienna
record_format MEDLINE/PubMed
spelling pubmed-101133562023-04-20 Lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology Zatloukalova, Martina Poltorak, Lukasz Bilewicz, Renata Vacek, Jan Mikrochim Acta Review Article Some biologically active substances are unstable and poorly soluble in aqueous media, at the same time exhibiting low bioavailability. The incorporation of these biologically active compounds into the structure of a lipid-based lyotropic liquid crystalline phase or nanoparticles can increase or improve their stability and transport properties, subsequent bioavailability, and applicability in general. The aim of this short overview is (1) to clarify the principle of self-assembly of lipidic amphiphilic molecules in an aqueous environment and (2) to present lipidic bicontinuous cubic and hexagonal phases and their current biosensing (with a focus on electrochemical protocols) and biomedical applications. GRAPHICAL ABSTRACT: [Image: see text] Springer Vienna 2023-04-18 2023 /pmc/articles/PMC10113356/ /pubmed/37071228 http://dx.doi.org/10.1007/s00604-023-05727-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Zatloukalova, Martina
Poltorak, Lukasz
Bilewicz, Renata
Vacek, Jan
Lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology
title Lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology
title_full Lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology
title_fullStr Lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology
title_full_unstemmed Lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology
title_short Lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology
title_sort lipid-based liquid crystalline materials in electrochemical sensing and nanocarrier technology
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113356/
https://www.ncbi.nlm.nih.gov/pubmed/37071228
http://dx.doi.org/10.1007/s00604-023-05727-w
work_keys_str_mv AT zatloukalovamartina lipidbasedliquidcrystallinematerialsinelectrochemicalsensingandnanocarriertechnology
AT poltoraklukasz lipidbasedliquidcrystallinematerialsinelectrochemicalsensingandnanocarriertechnology
AT bilewiczrenata lipidbasedliquidcrystallinematerialsinelectrochemicalsensingandnanocarriertechnology
AT vacekjan lipidbasedliquidcrystallinematerialsinelectrochemicalsensingandnanocarriertechnology

Ejemplares similares