Expansion of human megakaryocyte-biased hematopoietic stem cells by biomimetic Microniche

Limited numbers of available hematopoietic stem cells (HSCs) limit the widespread use of HSC-based therapies. Expansion systems for functional heterogenous HSCs remain to be optimized. Here, we present a convenient strategy for human HSC expansion based on a biomimetic Microniche. After demonstratin...

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Detalles Bibliográficos
Autores principales: Li, Yinghui, He, Mei, Zhang, Wenshan, Liu, Wei, Xu, Hui, Yang, Ming, Zhang, Hexiao, Liang, Haiwei, Li, Wenjing, Wu, Zhaozhao, Fu, Weichao, Xu, Shiqi, Liu, Xiaolei, Fan, Sibin, Zhou, Liwei, Wang, Chaoqun, Zhang, Lele, Li, Yafang, Gu, Jiali, Yin, Jingjing, Zhang, Yiran, Xia, Yonghui, Mao, Xuemei, Cheng, Tao, Shi, Jun, Du, Yanan, Gao, Yingdai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113370/
https://www.ncbi.nlm.nih.gov/pubmed/37072407
http://dx.doi.org/10.1038/s41467-023-37954-3

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