Statistical control of structural networks with limited interventions to minimize cellular phenotypic diversity represented by point attractors

The underlying genetic networks of cells give rise to diverse behaviors known as phenotypes. Control of this cellular phenotypic diversity (CPD) may reveal key targets that govern differentiation during development or drug resistance in cancer. This work establishes an approach to control CPD that e...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jongwan, Hopper, Corbin, Cho, Kwang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113376/
https://www.ncbi.nlm.nih.gov/pubmed/37072458
http://dx.doi.org/10.1038/s41598-023-33346-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113376/
https://www.ncbi.nlm.nih.gov/pubmed/37072458
http://dx.doi.org/10.1038/s41598-023-33346-1

Ejemplares similares