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Statistical control of structural networks with limited interventions to minimize cellular phenotypic diversity represented by point attractors
The underlying genetic networks of cells give rise to diverse behaviors known as phenotypes. Control of this cellular phenotypic diversity (CPD) may reveal key targets that govern differentiation during development or drug resistance in cancer. This work establishes an approach to control CPD that e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113376/ https://www.ncbi.nlm.nih.gov/pubmed/37072458 http://dx.doi.org/10.1038/s41598-023-33346-1 |