Different configurations of SARS-CoV-2 spike protein delivered by integrase-defective lentiviral vectors induce persistent functional immune responses, characterized by distinct immunogenicity profiles

Several COVID-19 vaccine strategies utilizing new formulations for the induction of neutralizing antibodies (nAbs) and T cell immunity are still under evaluation in preclinical and clinical studies. Here we used Simian Immunodeficiency Virus (SIV)-based integrase defective lentiviral vector (IDLV) d...

Descripción completa

Detalles Bibliográficos
Autores principales: Borghi, Martina, Gallinaro, Alessandra, Pirillo, Maria Franca, Canitano, Andrea, Michelini, Zuleika, De Angelis, Maria Laura, Cecchetti, Serena, Tinari, Antonella, Falce, Chiara, Mariotti, Sabrina, Capocefalo, Antonio, Chiantore, Maria Vincenza, Iacobino, Angelo, Di Virgilio, Antonio, van Gils, Marit J., Sanders, Rogier W., Lo Presti, Alessandra, Nisini, Roberto, Negri, Donatella, Cara, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113491/
https://www.ncbi.nlm.nih.gov/pubmed/37090707
http://dx.doi.org/10.3389/fimmu.2023.1147953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113491/
https://www.ncbi.nlm.nih.gov/pubmed/37090707
http://dx.doi.org/10.3389/fimmu.2023.1147953

Ejemplares similares