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Methylthioadenosine phosphorylase deficiency in tumors: A compelling therapeutic target

The methionine salvage pathway is responsible for recycling sulfur-containing metabolites to methionine. This salvage pathway has been found to be implicated in cell apoptosis, proliferation, differentiation and inflammatory response. Methylthioadenosine phosphorylase (MTAP) catalyzes the reversible...

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Detalles Bibliográficos
Autores principales:	Fan, Na, Zhang, Yi, Zou, Suyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113547/ https://www.ncbi.nlm.nih.gov/pubmed/37091983 http://dx.doi.org/10.3389/fcell.2023.1173356

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