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Immunological imprinting: Understanding COVID-19

Immunological imprinting generically refers to the effects prior exposures have on subsequent immune responses to, and eventually protection against, antigenically related viruses. Here, Koutsakos and Ellebedy explain different concepts and terms around imprinting and the fundamental immunological p...

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Detalles Bibliográficos
Autores principales: Koutsakos, Marios, Ellebedy, Ali H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113596/
https://www.ncbi.nlm.nih.gov/pubmed/37105169
http://dx.doi.org/10.1016/j.immuni.2023.04.012
Descripción
Sumario:Immunological imprinting generically refers to the effects prior exposures have on subsequent immune responses to, and eventually protection against, antigenically related viruses. Here, Koutsakos and Ellebedy explain different concepts and terms around imprinting and the fundamental immunological principles behind it. They also discuss the potential role imprinting may have in the context of COVID-19 vaccines.