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Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis
OBJECTIVES: The leading cause of mortality in patients with rheumatoid arthritis is atherosclerotic cardiovascular disease (CVD). We have shown that murine arthritis impairs atherosclerotic lesion regression, because of cellular cholesterol efflux defects in haematopoietic stem and progenitor cells...
Autores principales: | Dragoljevic, Dragana, Lee, Man Kit Sam, Pernes, Gerard, Morgan, Pooranee K, Louis, Cynthia, Shihata, Waled, Huynh, Kevin, Kochetkova, Arina A, Bell, Patrick W, Mellett, Natalie A, Meikle, Peter J, Lancaster, Graeme I, Kraakman, Michael J, Nagareddy, Prabhakara R, Hanaoka, Beatriz Y, Wicks, Ian P, Murphy, Andrew J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113696/ https://www.ncbi.nlm.nih.gov/pubmed/37091327 http://dx.doi.org/10.1002/cti2.1446 |
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