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Commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation

BACKGROUND: The setup of lung shield (LS) in total body irradiation (TBI) with the computed radiography (CR) system is a time‐consuming task and has not been quantitatively evaluated. The TBI mobile imager (TBI‐MI) can solve this problem through real‐time monitoring. Therefore, this study aimed to p...

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Autores principales: Nakaichi, Tetsu, Okamoto, Hiroyuki, Kon, Mitsuhiro, Takaso, Kazuki, Aikawa, Ako, Nakamura, Satoshi, Ijima, Kotaro, Chiba, Takahito, Nakayama, Hiroki, Takemori, Mihiro, Mikasa, Shohei, Fujii, Kyohei, Urago, Yuka, Goka, Tomonori, Shimizu, Yuri, Igaki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113699/
https://www.ncbi.nlm.nih.gov/pubmed/36573258
http://dx.doi.org/10.1002/acm2.13865
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author Nakaichi, Tetsu
Okamoto, Hiroyuki
Kon, Mitsuhiro
Takaso, Kazuki
Aikawa, Ako
Nakamura, Satoshi
Ijima, Kotaro
Chiba, Takahito
Nakayama, Hiroki
Takemori, Mihiro
Mikasa, Shohei
Fujii, Kyohei
Urago, Yuka
Goka, Tomonori
Shimizu, Yuri
Igaki, Hiroshi
author_facet Nakaichi, Tetsu
Okamoto, Hiroyuki
Kon, Mitsuhiro
Takaso, Kazuki
Aikawa, Ako
Nakamura, Satoshi
Ijima, Kotaro
Chiba, Takahito
Nakayama, Hiroki
Takemori, Mihiro
Mikasa, Shohei
Fujii, Kyohei
Urago, Yuka
Goka, Tomonori
Shimizu, Yuri
Igaki, Hiroshi
author_sort Nakaichi, Tetsu
collection PubMed
description BACKGROUND: The setup of lung shield (LS) in total body irradiation (TBI) with the computed radiography (CR) system is a time‐consuming task and has not been quantitatively evaluated. The TBI mobile imager (TBI‐MI) can solve this problem through real‐time monitoring. Therefore, this study aimed to perform commissioning and performance evaluation of TBI‐MI to promote its use in clinical practice. METHODS: The source‐axis distance in TBI treatment, TBI‐MI (CNERGY TBI, Cablon Medical B.V.), and the LS position were set to 400, 450, and 358 cm, respectively. The evaluation items were as follows: accuracy of image scaling and measured displacement error of LS, image quality (linearity, signal‐to‐noise ratio, and modulation transfer function) using an EPID QC phantom, optimal thresholding to detect intra‐fractional motion in the alert function, and the scatter radiation dose from TBI‐MI. RESULTS: The accuracy of image scaling and the difference in measured displacement of the LS was <4 mm in any displacements and directions. The image quality of TBI imager was slightly inferior to the CR image but was visually acceptable in clinical practice. The signal‐to‐noise ratio was improved at high dose rate. The optimal thresholding value to detect a 10‐mm body displacement was determined to be approximately 5.0%. The maximum fraction of scattering radiation to irradiated dose was 1.7% at patient surface. CONCLUSION: MI‐TBI can quantitatively evaluate LS displacement with acceptable image quality. Furthermore, real‐time monitoring with alert function to detect intrafraction patient displacement can contribute to safe TBI treatment.
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spelling pubmed-101136992023-04-20 Commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation Nakaichi, Tetsu Okamoto, Hiroyuki Kon, Mitsuhiro Takaso, Kazuki Aikawa, Ako Nakamura, Satoshi Ijima, Kotaro Chiba, Takahito Nakayama, Hiroki Takemori, Mihiro Mikasa, Shohei Fujii, Kyohei Urago, Yuka Goka, Tomonori Shimizu, Yuri Igaki, Hiroshi J Appl Clin Med Phys Radiation Oncology Physics BACKGROUND: The setup of lung shield (LS) in total body irradiation (TBI) with the computed radiography (CR) system is a time‐consuming task and has not been quantitatively evaluated. The TBI mobile imager (TBI‐MI) can solve this problem through real‐time monitoring. Therefore, this study aimed to perform commissioning and performance evaluation of TBI‐MI to promote its use in clinical practice. METHODS: The source‐axis distance in TBI treatment, TBI‐MI (CNERGY TBI, Cablon Medical B.V.), and the LS position were set to 400, 450, and 358 cm, respectively. The evaluation items were as follows: accuracy of image scaling and measured displacement error of LS, image quality (linearity, signal‐to‐noise ratio, and modulation transfer function) using an EPID QC phantom, optimal thresholding to detect intra‐fractional motion in the alert function, and the scatter radiation dose from TBI‐MI. RESULTS: The accuracy of image scaling and the difference in measured displacement of the LS was <4 mm in any displacements and directions. The image quality of TBI imager was slightly inferior to the CR image but was visually acceptable in clinical practice. The signal‐to‐noise ratio was improved at high dose rate. The optimal thresholding value to detect a 10‐mm body displacement was determined to be approximately 5.0%. The maximum fraction of scattering radiation to irradiated dose was 1.7% at patient surface. CONCLUSION: MI‐TBI can quantitatively evaluate LS displacement with acceptable image quality. Furthermore, real‐time monitoring with alert function to detect intrafraction patient displacement can contribute to safe TBI treatment. John Wiley and Sons Inc. 2022-12-26 /pmc/articles/PMC10113699/ /pubmed/36573258 http://dx.doi.org/10.1002/acm2.13865 Text en © 2022 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Nakaichi, Tetsu
Okamoto, Hiroyuki
Kon, Mitsuhiro
Takaso, Kazuki
Aikawa, Ako
Nakamura, Satoshi
Ijima, Kotaro
Chiba, Takahito
Nakayama, Hiroki
Takemori, Mihiro
Mikasa, Shohei
Fujii, Kyohei
Urago, Yuka
Goka, Tomonori
Shimizu, Yuri
Igaki, Hiroshi
Commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation
title Commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation
title_full Commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation
title_fullStr Commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation
title_full_unstemmed Commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation
title_short Commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation
title_sort commissioning and performance evaluation of commercially available mobile imager for image guided total body irradiation
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113699/
https://www.ncbi.nlm.nih.gov/pubmed/36573258
http://dx.doi.org/10.1002/acm2.13865
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