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Escaping ESKAPE resistance: in vitro and in silico studies of multifunctional carbamimidoyl-tethered indoles against antibiotic-resistant bacteria

Combining the hybridization and repurposing strategies, six compounds from our in-house library and having a designed hybrid structure of MBX-1162, pentamidine and MMV688271 were repurposed as potential antibacterial agents. Among, compounds 1a and 1d elicited potential sub-µg ml(−1) activity agains...

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Detalles Bibliográficos
Autores principales:	Gulia, Kanika, Hassan, Ahmed H. E., Lenhard, Justin R., Farahat, Abdelbasset A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113819/ https://www.ncbi.nlm.nih.gov/pubmed/37090961 http://dx.doi.org/10.1098/rsos.230020

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