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Side Effects Comparison of Coronavirus Vaccines Among Healthcare Workers in Shoushtar, Iran
OBJECTIVE: Vaccination is one of the effective ways to fight against COVID-19 disease. Various vaccines have been designed during the coronavirus pandemic. Each of the used vaccines has beneficial effects as well as side effects. Healthcare workers were among the first vaccinated persons against COV...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113905/ https://www.ncbi.nlm.nih.gov/pubmed/37155553 http://dx.doi.org/10.1177/2632010X231166798 |
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author | Nabizadeh, Edris Honarmandpour, Fatemeh Mashhadizade, Rezvan Honarmandpour, Azam |
author_facet | Nabizadeh, Edris Honarmandpour, Fatemeh Mashhadizade, Rezvan Honarmandpour, Azam |
author_sort | Nabizadeh, Edris |
collection | PubMed |
description | OBJECTIVE: Vaccination is one of the effective ways to fight against COVID-19 disease. Various vaccines have been designed during the coronavirus pandemic. Each of the used vaccines has beneficial effects as well as side effects. Healthcare workers were among the first vaccinated persons against COVID-19 in different countries. The current study aims to compare the side effects of AstraZeneca, Sinopharm, Bharat, and Sputnik V on healthcare workers in Iran. METHODS: This descriptive study was conducted from July 2021 to January 2022 on 1639 healthcare workers who received the COVID-19 vaccines. Data were collected using a checklist that contained questions related to systemic, local, and severe side effects of the vaccine. The collected data were analyzed using the Kruskal-Wallis, Chi-square, and trend chi-square. P < .05 was regarded as a significant statistical difference. RESULTS: The most commonly injected vaccines were Sinopharm (41.80%), Sputnik V (36.65%), AstraZeneca (17.75%), and Bharat (3.80%), respectively. At least 37.5% of participants reported one complication. The most common side effects after 72 hours of the first and second doses were as follows: injection site pain, fatigue, fever, myalgia, headache, and chill. Overall complication rates were reported as follows: AstraZeneca (91.4%), Sputnik V (65.9%), Sinopharm (56.8%), and Bharat (98.4%). Bharat showed the highest overall side effects, while Sinopharm had the lowest overall side effects. Also, our results indicated that individuals with a previous history of positive COVID-19 infection had a higher rate of overall complications. CONCLUSIONS: The majority of participants did not show life-threatening side effects after the injection of 1 of the 4 studied vaccines. Since it was well accepted and tolerable by the participants, it can be used widely and safely against SARS-CoV-2. |
format | Online Article Text |
id | pubmed-10113905 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-101139052023-04-24 Side Effects Comparison of Coronavirus Vaccines Among Healthcare Workers in Shoushtar, Iran Nabizadeh, Edris Honarmandpour, Fatemeh Mashhadizade, Rezvan Honarmandpour, Azam Clin Pathol Original Research OBJECTIVE: Vaccination is one of the effective ways to fight against COVID-19 disease. Various vaccines have been designed during the coronavirus pandemic. Each of the used vaccines has beneficial effects as well as side effects. Healthcare workers were among the first vaccinated persons against COVID-19 in different countries. The current study aims to compare the side effects of AstraZeneca, Sinopharm, Bharat, and Sputnik V on healthcare workers in Iran. METHODS: This descriptive study was conducted from July 2021 to January 2022 on 1639 healthcare workers who received the COVID-19 vaccines. Data were collected using a checklist that contained questions related to systemic, local, and severe side effects of the vaccine. The collected data were analyzed using the Kruskal-Wallis, Chi-square, and trend chi-square. P < .05 was regarded as a significant statistical difference. RESULTS: The most commonly injected vaccines were Sinopharm (41.80%), Sputnik V (36.65%), AstraZeneca (17.75%), and Bharat (3.80%), respectively. At least 37.5% of participants reported one complication. The most common side effects after 72 hours of the first and second doses were as follows: injection site pain, fatigue, fever, myalgia, headache, and chill. Overall complication rates were reported as follows: AstraZeneca (91.4%), Sputnik V (65.9%), Sinopharm (56.8%), and Bharat (98.4%). Bharat showed the highest overall side effects, while Sinopharm had the lowest overall side effects. Also, our results indicated that individuals with a previous history of positive COVID-19 infection had a higher rate of overall complications. CONCLUSIONS: The majority of participants did not show life-threatening side effects after the injection of 1 of the 4 studied vaccines. Since it was well accepted and tolerable by the participants, it can be used widely and safely against SARS-CoV-2. SAGE Publications 2023-04-19 /pmc/articles/PMC10113905/ /pubmed/37155553 http://dx.doi.org/10.1177/2632010X231166798 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Nabizadeh, Edris Honarmandpour, Fatemeh Mashhadizade, Rezvan Honarmandpour, Azam Side Effects Comparison of Coronavirus Vaccines Among Healthcare Workers in Shoushtar, Iran |
title | Side Effects Comparison of Coronavirus Vaccines Among Healthcare Workers in Shoushtar, Iran |
title_full | Side Effects Comparison of Coronavirus Vaccines Among Healthcare Workers in Shoushtar, Iran |
title_fullStr | Side Effects Comparison of Coronavirus Vaccines Among Healthcare Workers in Shoushtar, Iran |
title_full_unstemmed | Side Effects Comparison of Coronavirus Vaccines Among Healthcare Workers in Shoushtar, Iran |
title_short | Side Effects Comparison of Coronavirus Vaccines Among Healthcare Workers in Shoushtar, Iran |
title_sort | side effects comparison of coronavirus vaccines among healthcare workers in shoushtar, iran |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113905/ https://www.ncbi.nlm.nih.gov/pubmed/37155553 http://dx.doi.org/10.1177/2632010X231166798 |
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