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Sepsis mortality and ICU length of stay after the implementation of an intensive care team in the emergency department

Emergency department patient boarding is associated with hospital mortality and increased hospital length of stay. The objective of the present study is to describe the impact of deploying an Intensive Care team in the ED and its association with sepsis mortality and ICU length of stay. Patients adm...

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Autores principales: Tuttle, Erin, Wang, Xuan, Modrykamien, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113981/
https://www.ncbi.nlm.nih.gov/pubmed/37074499
http://dx.doi.org/10.1007/s11739-023-03265-0
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author Tuttle, Erin
Wang, Xuan
Modrykamien, Ariel
author_facet Tuttle, Erin
Wang, Xuan
Modrykamien, Ariel
author_sort Tuttle, Erin
collection PubMed
description Emergency department patient boarding is associated with hospital mortality and increased hospital length of stay. The objective of the present study is to describe the impact of deploying an Intensive Care team in the ED and its association with sepsis mortality and ICU length of stay. Patients admitted to ICU through the ED with an ICD-10 CM diagnosis of sepsis were included. Preintervention and postintervention phases included 4 and 15 months, respectively. Sepsis time zero, SEP-1 compliance, and lag time from time zero to antibiotic administration were compared. Outcomes of interest were mortality and ICU LOS. 1021 septic patients were included. Sixty-six percent fulfilled compliance with 3 h SEP-1 bundle. Lag time from time zero to antibiotic administration was 75 min. Multivariate analysis showed no association between ICU team in the ED and hospital mortality (Log OR 0.94, CI 0.67–1.34; p = 0.73). The ICU team in the ED was associated with prolonged ICU LOS (Log OR 1.21, CI 1.13–1.30; p < 0.01). Septic shock and ED boarding time were associated with prolonged ICU LOS. Compliance with SEP-1 bundle was associated with its reduction. Implementation of an ICU team in the ED for the treatment of septic patients during high volume hospitalizations is not associated with a reduction of mortality or ICU LOS.
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spelling pubmed-101139812023-04-20 Sepsis mortality and ICU length of stay after the implementation of an intensive care team in the emergency department Tuttle, Erin Wang, Xuan Modrykamien, Ariel Intern Emerg Med EM - Original Emergency department patient boarding is associated with hospital mortality and increased hospital length of stay. The objective of the present study is to describe the impact of deploying an Intensive Care team in the ED and its association with sepsis mortality and ICU length of stay. Patients admitted to ICU through the ED with an ICD-10 CM diagnosis of sepsis were included. Preintervention and postintervention phases included 4 and 15 months, respectively. Sepsis time zero, SEP-1 compliance, and lag time from time zero to antibiotic administration were compared. Outcomes of interest were mortality and ICU LOS. 1021 septic patients were included. Sixty-six percent fulfilled compliance with 3 h SEP-1 bundle. Lag time from time zero to antibiotic administration was 75 min. Multivariate analysis showed no association between ICU team in the ED and hospital mortality (Log OR 0.94, CI 0.67–1.34; p = 0.73). The ICU team in the ED was associated with prolonged ICU LOS (Log OR 1.21, CI 1.13–1.30; p < 0.01). Septic shock and ED boarding time were associated with prolonged ICU LOS. Compliance with SEP-1 bundle was associated with its reduction. Implementation of an ICU team in the ED for the treatment of septic patients during high volume hospitalizations is not associated with a reduction of mortality or ICU LOS. Springer International Publishing 2023-04-19 /pmc/articles/PMC10113981/ /pubmed/37074499 http://dx.doi.org/10.1007/s11739-023-03265-0 Text en © The Author(s), under exclusive licence to Società Italiana di Medicina Interna (SIMI) 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle EM - Original
Tuttle, Erin
Wang, Xuan
Modrykamien, Ariel
Sepsis mortality and ICU length of stay after the implementation of an intensive care team in the emergency department
title Sepsis mortality and ICU length of stay after the implementation of an intensive care team in the emergency department
title_full Sepsis mortality and ICU length of stay after the implementation of an intensive care team in the emergency department
title_fullStr Sepsis mortality and ICU length of stay after the implementation of an intensive care team in the emergency department
title_full_unstemmed Sepsis mortality and ICU length of stay after the implementation of an intensive care team in the emergency department
title_short Sepsis mortality and ICU length of stay after the implementation of an intensive care team in the emergency department
title_sort sepsis mortality and icu length of stay after the implementation of an intensive care team in the emergency department
topic EM - Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113981/
https://www.ncbi.nlm.nih.gov/pubmed/37074499
http://dx.doi.org/10.1007/s11739-023-03265-0
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