What Kept Back on the Mirror of COVID-19-Related Acute Transverse Myelitis? A Genetic Background!

COVID-19-associated acute transverse myelitis (ATM) cases have been reported worldwide. Nevertheless, Iran, Italy, and the USA are the most affected countries, witnessing the possibility that genetic factors might be associated with this susceptibility. The genetic variants of the coronavirus-2 entr...

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Autores principales: SINAEI, Reza, PEZESHKI, Sara, SINAEI, Roya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Beheshti University of Medical Sciences 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114267/
https://www.ncbi.nlm.nih.gov/pubmed/37091460
http://dx.doi.org/10.22037/ijcn.v17i2.36487
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author SINAEI, Reza
PEZESHKI, Sara
SINAEI, Roya
author_facet SINAEI, Reza
PEZESHKI, Sara
SINAEI, Roya
author_sort SINAEI, Reza
collection PubMed
description COVID-19-associated acute transverse myelitis (ATM) cases have been reported worldwide. Nevertheless, Iran, Italy, and the USA are the most affected countries, witnessing the possibility that genetic factors might be associated with this susceptibility. The genetic variants of the coronavirus-2 entry mechanisms and host innate immune response-related genes like interferons, interleukins, Toll-like receptors, human leukocyte antigens, blood groups, and some risk loci may be accountable. This study describes the compatibility of the geographical distribution between ATM and the Neanderthal core haplotype that confers risk for severe COVID-19 and some possible culprit genes.
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spelling pubmed-101142672023-06-01 What Kept Back on the Mirror of COVID-19-Related Acute Transverse Myelitis? A Genetic Background! SINAEI, Reza PEZESHKI, Sara SINAEI, Roya Iran J Child Neurol Case Report COVID-19-associated acute transverse myelitis (ATM) cases have been reported worldwide. Nevertheless, Iran, Italy, and the USA are the most affected countries, witnessing the possibility that genetic factors might be associated with this susceptibility. The genetic variants of the coronavirus-2 entry mechanisms and host innate immune response-related genes like interferons, interleukins, Toll-like receptors, human leukocyte antigens, blood groups, and some risk loci may be accountable. This study describes the compatibility of the geographical distribution between ATM and the Neanderthal core haplotype that confers risk for severe COVID-19 and some possible culprit genes. Shahid Beheshti University of Medical Sciences 2023 2023-03-15 /pmc/articles/PMC10114267/ /pubmed/37091460 http://dx.doi.org/10.22037/ijcn.v17i2.36487 Text en https://creativecommons.org/licenses/by-nc/4.0/This work is published as an open access article distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Case Report
SINAEI, Reza
PEZESHKI, Sara
SINAEI, Roya
What Kept Back on the Mirror of COVID-19-Related Acute Transverse Myelitis? A Genetic Background!
title What Kept Back on the Mirror of COVID-19-Related Acute Transverse Myelitis? A Genetic Background!
title_full What Kept Back on the Mirror of COVID-19-Related Acute Transverse Myelitis? A Genetic Background!
title_fullStr What Kept Back on the Mirror of COVID-19-Related Acute Transverse Myelitis? A Genetic Background!
title_full_unstemmed What Kept Back on the Mirror of COVID-19-Related Acute Transverse Myelitis? A Genetic Background!
title_short What Kept Back on the Mirror of COVID-19-Related Acute Transverse Myelitis? A Genetic Background!
title_sort what kept back on the mirror of covid-19-related acute transverse myelitis? a genetic background!
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114267/
https://www.ncbi.nlm.nih.gov/pubmed/37091460
http://dx.doi.org/10.22037/ijcn.v17i2.36487
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