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A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design

Distinct CD4(+) T cell epitopes have been associated with spontaneous control of HIV-1 replication, but analysis of antigen-dependent factors that influence epitope selection is lacking. To examine these factors, we used a cell-free antigen processing system that incorporates soluble HLA-DR (DR1), H...

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Detalles Bibliográficos
Autores principales: Sengupta, Srona, Zhang, Josephine, Reed, Madison C., Yu, Jeanna, Kim, Aeryon, Boronina, Tatiana N., Board, Nathan L., Wrabl, James O., Shenderov, Kevin, Welsh, Robin A., Yang, Weiming, Timmons, Andrew E., Hoh, Rebecca, Cole, Robert N., Deeks, Steven G., Siliciano, Janet D., Siliciano, Robert F., Sadegh-Nasseri, Scheherazade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114365/
https://www.ncbi.nlm.nih.gov/pubmed/37058141
http://dx.doi.org/10.1084/jem.20221654