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A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design
Distinct CD4(+) T cell epitopes have been associated with spontaneous control of HIV-1 replication, but analysis of antigen-dependent factors that influence epitope selection is lacking. To examine these factors, we used a cell-free antigen processing system that incorporates soluble HLA-DR (DR1), H...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114365/ https://www.ncbi.nlm.nih.gov/pubmed/37058141 http://dx.doi.org/10.1084/jem.20221654 |