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A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design
Distinct CD4(+) T cell epitopes have been associated with spontaneous control of HIV-1 replication, but analysis of antigen-dependent factors that influence epitope selection is lacking. To examine these factors, we used a cell-free antigen processing system that incorporates soluble HLA-DR (DR1), H...
Autores principales: | Sengupta, Srona, Zhang, Josephine, Reed, Madison C., Yu, Jeanna, Kim, Aeryon, Boronina, Tatiana N., Board, Nathan L., Wrabl, James O., Shenderov, Kevin, Welsh, Robin A., Yang, Weiming, Timmons, Andrew E., Hoh, Rebecca, Cole, Robert N., Deeks, Steven G., Siliciano, Janet D., Siliciano, Robert F., Sadegh-Nasseri, Scheherazade |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114365/ https://www.ncbi.nlm.nih.gov/pubmed/37058141 http://dx.doi.org/10.1084/jem.20221654 |
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