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Mesenchymal–epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expression

BACKGROUND: Oral squamous cell carcinoma (OSCC), an HPV-negative head and neck cancer, frequently metastasizes to the regional lymph nodes but only occasionally beyond. Initial phases of metastasis are associated with an epithelial–mesenchymal transition (EMT), while the consolidation phase is assoc...

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Detalles Bibliográficos
Autores principales: Horny, Kai, Sproll, Christoph, Peiffer, Lukas, Furtmann, Frauke, Gerhardt, Patricia, Gravemeyer, Jan, Stoecklein, Nikolas H., Spassova, Ivelina, Becker, Jürgen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114373/
https://www.ncbi.nlm.nih.gov/pubmed/37076857
http://dx.doi.org/10.1186/s12967-023-04102-w