Cargando…
Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study
BACKGROUND: Dual Energy Computed Tomography (DECT) is a technology that allows for viewing computed tomography spectral images. This method, due to ability of presenting specific elements and substances (like water, calcium and iodine), can be used to locate selected type of tissues. Thyroid tissue...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114424/ https://www.ncbi.nlm.nih.gov/pubmed/37072868 http://dx.doi.org/10.1186/s40644-023-00555-w |
_version_ | 1785028012731793408 |
---|---|
author | Durma, Adam Daniel Saracyn, Marek Zegadło, Arkadiusz Kamiński, Grzegorz |
author_facet | Durma, Adam Daniel Saracyn, Marek Zegadło, Arkadiusz Kamiński, Grzegorz |
author_sort | Durma, Adam Daniel |
collection | PubMed |
description | BACKGROUND: Dual Energy Computed Tomography (DECT) is a technology that allows for viewing computed tomography spectral images. This method, due to ability of presenting specific elements and substances (like water, calcium and iodine), can be used to locate selected type of tissues. Thyroid tissue due to being rich in endogenous iodine, can be located even without administration of contrast agent. CASE PRESENTATION: In presented cases authors used a feature of accumulating endogenous iodine in thyroid derivative tissue for diagnosis of differentiated thyroid cancer metastases. In Patient One DECT was a decisive parameter qualifying for the surgery. Due to use of DECT in Patient Two it was possible to directly localize thyroid cancer metastases, which was unfeasible using standard techniques (scintigraphy and [(18) F]FDG PET/CT). It helped to perform targeted biopsy and confirm diagnosis of thyroid cancer metastases, allowing to introduce treatment with sorafenibe. CONCLUSION: DECT confirmed its utility in locating thyroid tissues, including differentiated thyroid cancer (DTC) metastases. The method could be used in the future, especially in borderline or ambiguous cases with no localization of DTC in ultrasonography, RAI scintigraphy, or [(18) F]FDG PET/CT, and among patients having contraindications for contrast-CT. |
format | Online Article Text |
id | pubmed-10114424 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-101144242023-04-20 Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study Durma, Adam Daniel Saracyn, Marek Zegadło, Arkadiusz Kamiński, Grzegorz Cancer Imaging Case Series BACKGROUND: Dual Energy Computed Tomography (DECT) is a technology that allows for viewing computed tomography spectral images. This method, due to ability of presenting specific elements and substances (like water, calcium and iodine), can be used to locate selected type of tissues. Thyroid tissue due to being rich in endogenous iodine, can be located even without administration of contrast agent. CASE PRESENTATION: In presented cases authors used a feature of accumulating endogenous iodine in thyroid derivative tissue for diagnosis of differentiated thyroid cancer metastases. In Patient One DECT was a decisive parameter qualifying for the surgery. Due to use of DECT in Patient Two it was possible to directly localize thyroid cancer metastases, which was unfeasible using standard techniques (scintigraphy and [(18) F]FDG PET/CT). It helped to perform targeted biopsy and confirm diagnosis of thyroid cancer metastases, allowing to introduce treatment with sorafenibe. CONCLUSION: DECT confirmed its utility in locating thyroid tissues, including differentiated thyroid cancer (DTC) metastases. The method could be used in the future, especially in borderline or ambiguous cases with no localization of DTC in ultrasonography, RAI scintigraphy, or [(18) F]FDG PET/CT, and among patients having contraindications for contrast-CT. BioMed Central 2023-04-18 /pmc/articles/PMC10114424/ /pubmed/37072868 http://dx.doi.org/10.1186/s40644-023-00555-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Series Durma, Adam Daniel Saracyn, Marek Zegadło, Arkadiusz Kamiński, Grzegorz Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study |
title | Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study |
title_full | Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study |
title_fullStr | Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study |
title_full_unstemmed | Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study |
title_short | Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study |
title_sort | utility of non-contrast dual energy computed tomography in diagnosis of differentiated thyroid cancer – two case study |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114424/ https://www.ncbi.nlm.nih.gov/pubmed/37072868 http://dx.doi.org/10.1186/s40644-023-00555-w |
work_keys_str_mv | AT durmaadamdaniel utilityofnoncontrastdualenergycomputedtomographyindiagnosisofdifferentiatedthyroidcancertwocasestudy AT saracynmarek utilityofnoncontrastdualenergycomputedtomographyindiagnosisofdifferentiatedthyroidcancertwocasestudy AT zegadłoarkadiusz utilityofnoncontrastdualenergycomputedtomographyindiagnosisofdifferentiatedthyroidcancertwocasestudy AT kaminskigrzegorz utilityofnoncontrastdualenergycomputedtomographyindiagnosisofdifferentiatedthyroidcancertwocasestudy |