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Targeting Oncogene Promoters and Ribosomal RNA Biogenesis by G-Quadruplex Binding Ligands Translate to Anticancer Activity

[Image: see text] G-Quadruplex (GQ) nucleic acids are promising therapeutic targets in anticancer research due to their structural robustness, polymorphism, and gene-regulatory functions. Here, we presented the structure–activity relationship of carbazole-based monocyanine ligands using region-speci...

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Detalles Bibliográficos
Autores principales: Venkata Suseela, Yelisetty, Sengupta, Pallabi, Roychowdhury, Tanaya, Panda, Suman, Talukdar, Sangita, Chattopadhyay, Samit, Chatterjee, Subhrangsu, Govindaraju, Thimmaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114666/
https://www.ncbi.nlm.nih.gov/pubmed/37101746
http://dx.doi.org/10.1021/acsbiomedchemau.1c00039

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