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Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story

Glucosinolates are a group of thioglucosides that belong to the class of plant nitrogen-containing natural products. So far, very little biological activity has been associated with intact glucosinolates. The hydrolysis of glucosinolates has, for long, attracted attention because of the potent biolo...

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Autores principales: Abdel-Massih, Roula M., Debs, Espérance, Othman, Leen, Attieh, Jihad, Cabrerizo, Franco M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114928/
https://www.ncbi.nlm.nih.gov/pubmed/37089539
http://dx.doi.org/10.3389/fmicb.2023.1130208
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author Abdel-Massih, Roula M.
Debs, Espérance
Othman, Leen
Attieh, Jihad
Cabrerizo, Franco M.
author_facet Abdel-Massih, Roula M.
Debs, Espérance
Othman, Leen
Attieh, Jihad
Cabrerizo, Franco M.
author_sort Abdel-Massih, Roula M.
collection PubMed
description Glucosinolates are a group of thioglucosides that belong to the class of plant nitrogen-containing natural products. So far, very little biological activity has been associated with intact glucosinolates. The hydrolysis of glucosinolates has, for long, attracted attention because of the potent biological activity of the hydrolysis products. From allelopathic to antiparasitic, antimicrobial and antineoplastic effects, the activity spectrum of the degradation products of typical glucosinolates has been the subject of much research. The present review seeks to address the various means of glucosinolate degradation (thermal, enzymatic, or chemical degradation) and the ensuing products. It also aims to draw a comparative profile of the various antimicrobial effects of these degradation products to provide a further understanding of the biological function of these important compounds.
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spelling pubmed-101149282023-04-20 Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story Abdel-Massih, Roula M. Debs, Espérance Othman, Leen Attieh, Jihad Cabrerizo, Franco M. Front Microbiol Microbiology Glucosinolates are a group of thioglucosides that belong to the class of plant nitrogen-containing natural products. So far, very little biological activity has been associated with intact glucosinolates. The hydrolysis of glucosinolates has, for long, attracted attention because of the potent biological activity of the hydrolysis products. From allelopathic to antiparasitic, antimicrobial and antineoplastic effects, the activity spectrum of the degradation products of typical glucosinolates has been the subject of much research. The present review seeks to address the various means of glucosinolate degradation (thermal, enzymatic, or chemical degradation) and the ensuing products. It also aims to draw a comparative profile of the various antimicrobial effects of these degradation products to provide a further understanding of the biological function of these important compounds. Frontiers Media S.A. 2023-04-05 /pmc/articles/PMC10114928/ /pubmed/37089539 http://dx.doi.org/10.3389/fmicb.2023.1130208 Text en Copyright © 2023 Abdel-Massih, Debs, Othman, Attieh and Cabrerizo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Abdel-Massih, Roula M.
Debs, Espérance
Othman, Leen
Attieh, Jihad
Cabrerizo, Franco M.
Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story
title Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story
title_full Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story
title_fullStr Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story
title_full_unstemmed Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story
title_short Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story
title_sort glucosinolates, a natural chemical arsenal: more to tell than the myrosinase story
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114928/
https://www.ncbi.nlm.nih.gov/pubmed/37089539
http://dx.doi.org/10.3389/fmicb.2023.1130208
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