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Lamin B1 overexpression alters chromatin organization and gene expression

Peripheral heterochromatin positioning depends on nuclear envelope associated proteins and repressive histone modifications. Here we show that overexpression (OE) of Lamin B1 (LmnB1) leads to the redistribution of peripheral heterochromatin into heterochromatic foci within the nucleoplasm. These cha...

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Detalles Bibliográficos
Autores principales:	Kaneshiro, Jeanae M., Capitanio, Juliana S., Hetzer, Martin W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114975/ https://www.ncbi.nlm.nih.gov/pubmed/37071033 http://dx.doi.org/10.1080/19491034.2023.2202548

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