Genetic regulatory and biological implications of the 10q24.32 schizophrenia risk locus

Genome-wide association studies have identified 10q24.32 as a robust schizophrenia risk locus. Here we identify a regulatory variant (rs10786700) that disrupts binding of transcription factors at 10q24.32. We independently confirmed the association between rs10786700 and schizophrenia in a large Chi...

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Detalles Bibliográficos
Autores principales: Wang, Junyang, Liu, Jiewei, Li, Shiwu, Li, Xiaoyan, Yang, Jinfeng, Dang, Xinglun, Mu, Changgai, Li, Yifan, Li, Kaiqin, Li, Jiao, Chen, Rui, Liu, Yixing, Huang, Di, Zhang, Zhijun, Luo, Xiong-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115178/
https://www.ncbi.nlm.nih.gov/pubmed/36152315
http://dx.doi.org/10.1093/brain/awac352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115178/
https://www.ncbi.nlm.nih.gov/pubmed/36152315
http://dx.doi.org/10.1093/brain/awac352

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